BJUI Mini Reviews - The influence of family history on prostate cancer risk: Implications for clinical management

BERKELEY, CA ( - Prostate cancer is the most frequently diagnosed cancer in men in Europe [1] and in the USA.[2]

Data from the USA, where PSA level testing and subsequent biopsy has become widespread, have shown that the lifetime probability of a man being diagnosed with invasive prostate cancer is 15.9% (1 in 6).[2] Given the high incidence and mortality associated with the disease, much focus has been placed in recent years on identifying risk factors for developing prostate cancer to help identify men who are at increased risk of being diagnosed with prostate cancer in the future. PSA has been shown to be the single most significant predictive factor for identifying men at increased risk of prostate cancer.[3]...View or save the Mini Review as a .pdf file.





Stephan Madersbacher,a Antonio Alcaraz,b Mark Emberton,c Peter Hammerer,d Anton Ponholzer,e Fritz H. Schröder,f and Andrea Tubarog
a Department of Urology and Andrology, Danube Hospital, Vienna, Austria, b Department of Urology, Hospital Clinic Department of Urology, Institut d’Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain, c Division of Surgery and Interventional Science, University College London (UCL) Hospitals NHS Foundation Trust/UCL Comprehensive Biomedical Research Centre, London, UK, d Department of Urology, Academic Hospital, Braunschweig, Germany, e Department of Urology and Andrology, Hospital St. John of God, Vienna, Austria, f Department of Urology, Erasmus Medical Center, University Medical Centre, Rotterdam, The Netherlands, and g Department of Urology, Sant’Andrea Hospital 2nd School of Medicine, ‘La Sapienza’ University of Rome, Rome, Italy


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