Disruptive events in the life of prostate cancer - Abstract

Michigan Center for Translational Pathology, University of Michigan 1400 E. Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA.

Department of Pathology, University of Michigan 1400 E. Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA; Program in Cellular and Molecular Biology, University of Michigan 1400 E. Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA.

 

 

Two recent reports in Nature provide evidence for increasingly complex "disruptive" molecular alterations that occur during prostate cancer progression. They shed light on the intricacy of genetic changes that modulate PTEN's control over the phosphoinositide 3-kinase pathway and prostate cancer progression, and identify new potential biomarkers and therapeutic targets.

Written by:
Brenner JC, Chinnaiyan AM.   Are you the author?

Reference: Cancer Cell. 2011 Mar 8;19(3):301-3.
doi: 10.1016/j.ccr.2011.02.020

PubMed Abstract
PMID: 21397854

UroToday.com Prostate Cancer Section


 

 

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