Endorectal MRI accuracy in auguring tumour location, tumour extent, capsular perforation and seminal vesicle invasion of prostate cancer in North-African men - Abstract

Department of Urology, Universitary Military Hospital Med V, Hay Ryad, Rabat, Morocco.

To assess the value of endorectal magnetic resonance imaging (eMRI) for detecting the tumour site, tumour size, and disease extent in north-African patients with localized prostatic adenocarcinoma.

The MRI findings were compared with the histopathologic parameters of radical prostatectomy specimens in 190 patients.

The histologic examination revealed 372 cancer foci. Endorectal MRI detected 218 cancer foci. The accuracy, sensitivity, and positive predictive value of endorectal MRI for detecting tumour foci greater than 1cm in diameter were 79.8%, 85.3%, and 92.6%, respectively. The corresponding values for detecting tumour foci smaller than 1cm were 24.2%, 26.2%, and 75.9%, respectively. The maximal tumour diameter on endorectal MRI correlated with that shown by histologic examination for tumours larger than 1cm in diameter. However, it did not correlate significantly with the histologic diameter of tumours smaller than 1cm. The accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of endorectal MRI were 74.7%, 57.1%, 82.1%, 57.1%, and 82.1%, respectively, for the detection of extracapsular extension and were 75.8%, 62.1%, 81.8%, 60.0%, and 83.1%, respectively, for local staging.

The results of the present study suggest that eMRI was useful for predicting local extension, as well as tumour site and tumour size, of cancer foci greater than 1cm in diameter.

Written by:
Janane A, Hajji F, Ismail TO, Elondo JC, Ghadouane M, Ameur A, Abbar M.   Are you the author?

Reference: Eur J Radiol. 2011 Jan 25. Epub ahead of print.

PubMed Abstract
PMID: 21273020

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