Prostatectomy in oligometastatic prostate cancer: a call for high-quality evidence.

The systematic review by Saouli et al. investigates the role of radical prostatectomy (RP) in managing oligometastatic prostate cancer (omPCa) [1]. They analyzed the existing literature to assess the oncological and functional outcomes of RP for these patients. RP is feasible and has an acceptable risk of complications. However, the lack of consensus on the definitions of omPCa and the low-quality evidence of the available comparative and retrospective studies, RP in omPCa should not be recommended outside of clinical trials.

Prostate cancer and prostatic diseases. 2024 Apr 20 [Epub ahead of print]

Tanya Dorff, Sheetal R Kashid, Vedang Murthy, Riccardo Lombardo, Cosimo De Nunzio

Department of Medical Oncology & Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India., Sapienza University, Rome, Italy., Sapienza University, Rome, Italy. .