Should Transperineal Prostate Biopsy Be the Standard of Care?

We reviewed the advantages and disadvantages of transperineal prostate biopsy (TP-bx) to evaluate its potential role as the standard of care for prostate biopsy.

Studies have suggested no difference in prostate cancer (PCa) detection rate between TP-bx and transrectal biopsy (TR-bx) but have suggested potentially increased detection of anterior prostate tumors. Advances in anesthetic technique have obviated the need for sedation thus allowing TP-bx to become an office-based procedure, which in turn can decrease the overall cost of TP-bx. Furthermore, given the low rate of infectious complications after TP-bx, some have foregone peri-procedural antibiotics without a change in the rate of infectious complications. Recent procedural advances have made TP-bx a tolerable, office-based procedure. Given the similar diagnostic performance and the benefits for the patient and community, TP-bx should become the standard of care for prostate biopsy for most patients. Future efforts should address the barriers for more universal adoption.

Current urology reports. 2022 Dec 13 [Epub ahead of print]

Rand N Wilcox Vanden Berg, Arvin K George, Deborah R Kaye

Division of Urology, Department of Surgery, Duke University, Durham, NC, USA., Department of Urology, University of Michigan, Ann Arbor, MI, USA., Division of Urology, Department of Surgery, Duke University, Durham, NC, USA. .