Prostate Cancer with Peritoneal Carcinomatosis: A robotic-assisted radical prostatectomy-based Case Series.

To aid in the diagnosis and treatment of patients with metastatic tumor seeding, an exceedingly phenomenon following minimally invasive urological surgery, additional case reports are needed.

We report our experience with patients determined to have peritoneal carcinomatosis following robotic-assisted radical prostatectomy (RARP) and provide a descriptive summary of these unique cases.

Five cases of peritoneal carcinomatosis were identified, all of which occurred relatively late - between 8-13 years - following RARP. Four of the five cases had T3 disease at the time of prostatectomy. 68Ga-PSMA PET identified peritoneal carcinomatosis in three of five cases.

Certain clinical factors, such as advanced pathologic stage at the time of prostatectomy, may predict risk for carcinomatosis following RARP. Additionally, next generation imaging modalities, such as PSMA PET, may aid in identifying these metastases and are likely to identify increasing numbers of these patients as next generation imaging becomes more widely available. Continued documentation and classification of this atypical presentation are needed to improve our understanding and management of this phenomenon.

Urology. 2022 Apr 23 [Epub ahead of print]

Steven B Goldenthal, Melissa A Reimers, Udit Singhal, Mark Farha, Rohit Mehra, Morand Piert, Jeffrey J Tosoian, Parth K Modi, Nicole Curci, James Peabody, Eduardo Kleer, David C Smith, Todd M Morgan

Department of Urology, University of Michigan, Ann Arbor, MI; Department of Urology, Ohio State Wexner Medical Center, Columbus, OH. Electronic address: ., Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Department of Urology, University of Michigan, Ann Arbor, MI; Mayo Clinic, Department of Urology, Rochester, MN., Department of Urology, University of Michigan, Ann Arbor, MI., Department of Pathology, University of Michigan, Ann Arbor, MI., Department of Radiology, University of Michigan, Ann Arbor, MI., Department of Urology, Henry Ford Health System, Detroit, MI., IHA Urology, St. Joseph Mercy Hospital, Ypsilanti, MI.

email news signup