There are very few articles comparing open radical prostatectomy (ORP) vs. laparoscopic radical prostatectomy (LRP) and their functional results or urinary continence (UC), which is one of the most important objectives to pursue after oncological results.
To compare postoperative UC in patients with localized prostatic adenocarcinoma treated with OPR or LRP.
Comparison between two patient cohorts (312 for ORP and 206 for LRP) between 2007-2015. The UC was evaluated at 3, 6, 12, 18 and 24months. Continence was defined and classified as follows: a)UC, no need of pads, and b)urinary incontinence (UI), use of pads. To compare the qualitative variables, we employed the chi-squared test and ANOVA for quantitative variables. We performed a multivariate analysis using logistic regression with dependent qualitative variable UI. Statistical significance when P<.05.
Nerve-sparing was performed in 51.7% cases. At 24months after surgery, 72.4% patients had UC, of which 87.7% were from the ORP group and 78.1% in the LRP group (P=.004). 22,7% of patients experienced biochemical recurrence (BR), with 83% treated with salvage radiotherapy (SRT), presenting greater UI percentage (P=.036). ORP patients showed a higher percentage of anastomosis stricture (P=.03).
LRP, non-nerve sparing, and SRT were directly related to postoperative UI.
Actas urologicas espanolas. 2020 Mar 06 [Epub ahead of print]
E Martínez-Holguín, F Herranz-Amo, E Lledó-García, J Ruiz-Bel, L Esteban-Labrador, D Subirá-Ríos, C Hernández-Fernández
Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: ., Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.