Survivorship care for patients with prostate cancer requires careful consideration of unique disease-specific factors, including the prolonged natural disease history, the potential for competing health risks, and the consequences of long-term androgen deprivation therapy. However, current prostate cancer survivorship research is unfortunately limited by the lack of a robust supportive evidence base, variability in the definitions and measurement of survivorship outcomes, and a heavy reliance on expert opinion. As a result, the conduct of quality prostate cancer survivorship research is of increasing importance for patients, medical providers, and other key stakeholders. This manuscript harmonizes a path forward for improving prostate cancer survivorship by defining prostate cancer survivorship and survivorship research, as well as by highlighting key research priorities and cooperative mechanisms for survivorship studies within prostate cancer, with a particular focus on men with advanced disease.
Urologic oncology. 2019 Nov 13 [Epub ahead of print]
Vivek Narayan, Michael Harrison, Heather Cheng, Stacey Kenfield, Rahul Aggarwal, Daniel Kwon, Rana McKay, Richard Hauger, Nicolas Hart, Suzanne Conzen, Hala Borno, Heather Jim, Adam Dicker, Tanya Dorff, Javid Moslehi, Lorelei Mucci, J Kellogg Parsons, Fred Saad, Howard Soule, Alicia Morgans, Charles J Ryan
Division of Hematology/Medical Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA., Duke University Medical Center, Durham, NC., University of Washington School of Medicine, Fred Hutchinson Cancer Research Center, Seattle, WA., Department of Urology, University of California San Francisco, San Francisco, CA., Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Department of Medicine, Division of Hematology/Oncology, University of California San Diego, San Diego, CA., Department of Psychiatry and Center for Behavior Genetics of Aging, University of California San Diego, San Diego, CA., School of Medical and Health Sciences, Exercise Medicine Research Institute, Edith Cowan University, Joondalup, Western Australia, Australia., Department of Medicine, University of Chicago, Chicago, IL., Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL., Department of Radiation Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA., Department of Medical Oncology and Developmental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA., Department of Medicine, Cardio-oncology Program, Vanderbilt University Medical Center, Nashville, TN., Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA., Department of Urology, Moores Comprehensive Cancer Center, University of California San Diego, San Diego, CA., Division of Urology, University of Montreal Health Center, Montreal, Quebec, Canada., Prostate Cancer Foundation, Santa Monica, CA., Department of Hematology and Oncology, Northwestern University, Chicago, IL., Division of Hematology, Medical Oncology, and Transplantation, University of Minnesota, Minneapolis, MN. Electronic address: .