To evaluate the use of radiotherapy (RT) for oligometastatic cancer (OMC) among radiation oncologists in Lombardy, Italy.
A survey with 12 items regarding data of 2016 was sent to all 34 Lombardy RT centers. The survey included six general items and six specific items regarding patient/disease/treatment characteristics.
Thirteen centers answered the survey (38%). All centers responded to general items and 12 centers submitted patient/disease/treatment data. General items The majority of centers (8/13) consider OMC if metastases number is less than 5. The most commonly prescribed dose/fraction is 5-10 Gy (8/13) using schedules of 3-5 fractions (11/13). Patient data items A total of 15.681 patients were treated in 2016 with external beam RT in 12 responding centers, and 1.087 patients were treated for OMC (7%). Primary tumor included lung, prostate, breast, colorectal and other malignancies in 33%, 21%, 12%, 9% and 25% of all OMC patients, respectively. Brain, lymph node, lung, bone, liver and others were the most common treated sites (24%, 24%, 22%, 17%, 8% and 5%, respectively). One and more than one metastasis were treated in 75 and 25% of patients, respectively. The vast majority of patients (95%) were treated with image-guided intensity-modulated RT or stereotactic RT.
Seven percent of all RT patients in Lombardy are treated for OMC. Extreme hypofractionation and high-precision RT are commonly employed. The initiative of multicenter and multidisciplinary collaboration has been undertaken in order to prepare the platform for prospective and/or observational studies in OMC.
La Radiologia medica. 2018 Dec 15 [Epub ahead of print]
Barbara Alicja Jereczek-Fossa, Barbara Bortolato, Marianna Alessandra Gerardi, Samantha Dicuonzo, Virginia Maria Arienti, Stefania Berlinghieri, Stefano Bracelli, Michela Buglione, Mariangela Caputo, Gianpiero Catalano, Luigi Franco Cazzaniga, Luigi De Cicco, Nadia Di Muzio, Francesco Romeo Filippone, Andrei Fodor, Davide Franceschini, Paolo Frata, Stefania Gottardo, Giovanni Battista Ivaldi, Antonio Laudati, Stefano Maria Magrini, Elisa Mantero, Ilaria Meaglia, Sara Morlino, Mauro Palazzi, Fabio Piccoli, Paola Romanelli, Marta Scorsetti, Flavia Serafini, Luciano Scandolaro, Riccardo Valdagni, Roberto Orecchia, Paolo Antognoni, Lombardy Section of the Italian Society of Oncological Radiotherapy (Associazione Italiana di Radioterapia Oncologica-Lombardia, AIRO-L)
Department of Radiation Oncology, European Institute of Oncology IRCCS, via Ripamonti 435, 20141, Milan, Italy., SC Radioterapia, ASST Ospedale Niguarda, Milan, Italy., Department of Radiation Oncology, European Institute of Oncology IRCCS, via Ripamonti 435, 20141, Milan, Italy. ., Servizio di Radioterapia Ospedale di Esine, ASST di Valcamonica, Esine, Italy., Division of Radiation Oncology, ASST of Olona Valley, Busto Arsizio, Italy., Radioterapia Oncologica, Università e Spedali Civili, Brescia, Italy., Radiation Oncology Unit, Department of Diagnostic Imaging and Radiotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., S.C. Radioterapia, IRCCS MultiMedica, Sesto San Giovanni, Milan, Italy., U.O.C. Radioterapia, ASST Papa Giovanni XXIII, Bergamo, Italy., Department of Radiotherapy, San Raffaele Scientific Institute, Milan, Italy., Radiotherapy and Radiosurgery Department, Humanitas Research Hospital and Cancer Center, Rozzano, Milan, Italy., Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Istituti Clinici Scientifici Maugeri Pavia, Pavia, Italy., UOC di Radioterapia Oncologica, ASST Lariana, Ospedale S. Anna, Como, Italy., S. C. Radioterapia, ASST dei Sette Laghi-Ospedale di Circolo e Fondazione Macchi, Varese, Italy.