Prostate Cancer Mortality rates in Peru and its geographic regions

Prostate cancer is the fifth most prevalent cause of cancer death in men worldwide. A recent report described the mortality rates for prostate cancer in Peru, but a comprehensive evaluation of variations in prostate cancer epidemiology by geographic areas has not been performed, yet. Our aim is to evaluate the mortality rates of prostate cancer, according to geographical areas in Peru, between 2005 and 2014.

Information was extracted from the Deceased Registry of the Peruvian Ministry of Health. We analysed age-standardized mortality rates (world population) per 100,000 men. Spatial autocorrelation was determined according to the Moran Index. In addition, we used Cluster Map to explore relations between departments.

Mortality rates increased from 20.9 (2005-2009) to 24.1 (2010-2014) per 100,000 men, an increase of 15.2%. According to regions, during the period 2010-2014, the coast had the highest mortality rate (28.9/100,000) while the rainforest had the lowest (7.43/100,000). In addition, there was an increase in mortality in the coast and a decline in the rainforest over the period 2005-2014. The departments with the highest mortality were Piura, Lambayeque, La Libertad, Callao, Lima, Ica, and Arequipa. Moreover, these departments (except Arequipa) showed increasing trends during the years under study. The departments with the lowest observed prostate cancer mortality rates were Loreto, Ucayali, and Madre de Dios. This study showed positive spatial autocorrelation (Moran's I: 0.30, p=0.01).

Mortality rates from prostate cancer in Peru continue to increase. These rates are higher in the coastal region compared to those from the highlands or rainforest. This article is protected by copyright. All rights reserved.

BJU international. 2018 Oct 03 [Epub ahead of print]

J Smith Torres-Roman, Eloy F Ruiz, Jose Fabian Martinez-Herrera, Sonia Faria Mendes Braga, Luis Taxa, Jorge Saldaña-Gallo, Mariela R Pow-Sang, Julio M Pow-Sang, Carlo La Vecchia

Clinica de Urologia Avanzada UROZEN, Lima, Peru., CONEVID Unidad de Conocimiento y Evidencia Universidad Peruana Cayetano Heredia, Lima, Peru., Cancer Center, Medical Center American British Cowdray, Mexico City, Mexico., Department of Social and Preventive Medicine Faculty of Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil., Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru., Department of Urology, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru., Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, Florida., Department of Clinical Sciences and Community Health, Universitá degli Studi di Milano, 20133, Milan, Italy.