Contrast-Enhanced Transrectal Ultrasound for Follow-up After Focal HIFU Ablation for Prostate Cancer

The optimal strategy for imaging after focal therapy for prostate cancer is evolving. This series is an initial report on the use of contrast-enhanced transrectal ultrasound (TRUS) in follow-up of patients after high-intensity focused ultrasound (HIFU) hemiablation for prostate cancer. In 7 patients who underwent HIFU hemiablation, contrast-enhanced TRUS findings were as follows: (1) contrast-enhanced TRUS clearly showed the HIFU ablation defect as a sharply marginated nonenhancing zone in all patients; (2) contrast-enhanced TRUS identified suspicious foci of recurrent enhancement within the ablation zone in 2 patients, facilitating image-guided prostate biopsy, which showed prostate cancer; and (3) contrast-enhanced TRUS findings correlated with multiparametric magnetic resonance imaging and biopsy histologic findings.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 2018 Aug 16 [Epub ahead of print]

Andre L de Castro Abreu, Akbar N Ashrafi, Inderbir S Gill, Masakatsu Oishi, Matthew W Winter, Daniel Park, Vinay Duddalwar, Mariana C Stern, Suzanne L Palmer, Manju Aron, Mittul Gulati

USC Institute of Urology, University of Southern California, Los Angeles, California, USA., Department of Radiology, University of Southern California, Los Angeles, California, USA., Department of Pathology, University of Southern California, Los Angeles, California, USA.