Excessive skeletal radioisotope uptake in relation to soft tissues along with absent or faint activity in the genitourinary tract on skeletal scintigraphy is known as a "superscan." Prostate cancer is the most common cause of superscan in skeletal scintigraphy due to diffuse skeletal metastases. However, prostate cancer may cause secondary renal osteodystrophy leading to metabolic superscan also. Differentiating between these two entities are important as treatment options are different. We, hereby, describe a case of prostatic adenocarcinoma presented with metabolic superscan on methylene diphosphonate skeletal scintigraphy and demonstrate the utility of single emission computed tomography-computed tomography in differentiating between two entities.
Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India. 0000 Jan [Epub]
Piyali Chatterjee, Anirban Mukherjee, Deepanjan Mitra, Amit Nautiyal, Anindya Roy
Department of Nuclear Medicine, AMRI Hospitals, Kolkata, West Bengal, India.