Surgical treatment of advanced penile cancer

To evaluate the therapeutic effect of surgery in patients with advanced penile cancer, who have a dismal prognosis.

Between September 2007 and July 2015, we treated 12 patients with surgical therapy.

The median follow-up period for all the patients was 16 months (range 4-60 months). The outcome and concomitant symptoms were analyzed, and the survival rates were calculated. Three of the patients are currently alive. The median overall survival of the patients was 9 months (range 4-13 months).

The present results suggest that surgery is a valuable treatment option for patients with advanced penile cancer. The prognosis of advanced penile cancer is closely related to lymph node and distant metastases. Flap repair can solve the problem of large area skin defect. Advanced penile cancer is difficult to treat regardless of chemotherapy or radiotherapy, and surgery cannot prolong the lives of patients. However, the dissection of lesions and repair of large area skin defects can dramatically improve the quality of life of patients, especially those with locally advanced disease without distant metastasis.

Journal of cancer research and clinical oncology. 2017 May 10 [Epub ahead of print]

Ke Zhang, Xiang Wan, Huan Xu, Wenzhi Li, Juan Zhou, Ming-Xi Xu, Hai-Jun Yao, Zhong Wang

Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No.639 of Zhizaoju Road in Huangpu District, Shanghai, 200011, China., Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No.639 of Zhizaoju Road in Huangpu District, Shanghai, 200011, China. ., Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No.639 of Zhizaoju Road in Huangpu District, Shanghai, 200011, China. .

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