Emerging Systemic Therapies for the Management of Penile Cancer.

Penile squamous cell carcinoma (PSCC) is a rare cancer, but is more common in developing countries. Locally advanced and metastatic PSCC is associated with significant morbidity and mortality, with the prognosis remaining extremely poor. The authors searched PubMed and published abstracts for metastatic PSCC studies to describe emerging therapies. Multimodality treatment using chemotherapy, radiation, and consolidative surgery are standard of care. Utilizing anti-EGFR therapies and novel immunotheraputic approaches may help improve outcomes in PSCC.

The Urologic clinics of North America. 2016 Sep 03 [Epub]

Shilpa Gupta, Guru Sonpavde

Department of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA., Section of Medical Oncology, Department of Medicine, UAB Comprehensive Cancer Center, 1802 6th Avenue South, NP2540B, Birmingham, AL 35294, USA. Electronic address: .