Expression of long noncoding RNA lncRNA-n336928 is correlated with tumor stage and grade and overall survival in bladder cancer

Long noncoding RNAs (lncRNAs) have been implicated playing important roles in human urologic cancers. In the present study, microarray analysis was initially performed to screen the differentially expressed lncRNAs between bladder cancer tissues and paired adjacent non-cancerous tissues (n=3).

Subsequent qRT-PCR validation was conducted using tissue samples from 95 patients with bladder cancer. Results showed that the expression level of lncRNA-n336928 (noncode database ID: n336928) was significantly higher in bladder cancer tissues compared to that in adjacent noncancerous tissues (P

Biochemical and biophysical research communications. 2015 Nov 06 [Epub ahead of print]

Tao Chen, Wanqin Xie, Linguo Xie, Yan Sun, Yu Zhang, Zhonghua Shen, Nan Sha, Hao Xu, Zhouliang Wu, Hailong Hu, Changli Wu

Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Key Laboratory of genetics and birth health of Hunan province, the family planning research institute of Hunan province, Changsha, Hunan 410126, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. , Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China. Department of Urology, the Second Hospital of Tianjin Medical University, Pingjiang Road 23, Hexi District, Tianjin 300211, China; Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China.  

PubMed