Integrating circulating tumor cell data with imaging and serum prostate-specific antigen measurement for metastatic prostate cancer therapy management - Abstract

Optimal management of therapy can improve quality of life, and potentially survival, of patients with metastatic prostate cancer. Circulating tumor cell (CTC) enumeration in the peripheral blood holds promise for facilitating optimal therapy management based on high cancer specificity and prompt response to changes in disease status. We present the case of a 54-year-old male diagnosed with metastatic prostate cancer. The patient's disease status was monitored radiographically and by serial determinations of serum prostate-specific antigen concentration, performance status, and CTC enumeration. At multiple visits, the disease status was not clear due to discordance between standard assessments. The additional information provided by CTC enumeration helped clarify disease status and provided support for treatment decisions.

Written by:
Goodman O, Schuur ER.   Are you the author?
Comprehensive Cancer Centers of Nevada, Las Vegas, Nev., USA; VMWA LLC, Palo Alto, Calif., USA; The Jon Block Group, San Francisco, Calif., USA.

Reference: Case Rep Oncol. 2014 Mar 22;7(1):217-21.
doi: 10.1159/000361042

PubMed Abstract
PMID: 24803898

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