The MAPK signaling pathway plays a key role in the differentiation, proliferation and apoptosis of cells, and its family members mainly include extracellular signal-regulated kinase (ERK), stress-activated protein kinase (JNK), and p38 mitogen-activated protein kinase (p38MAPK). Recent studies have shown that the ERK, JNK and p38MAPK signaling pathways are closely associated with the development and progression of erectile dysfunction (ED). This review focuses on the correlation between the MAPK signaling pathway and ED.
Zhonghua nan ke xue = National journal of andrology. 2018 May [Epub]
Si-Xiang Chen, Fan Zhao, Xiao-Jun Huang
The Second School of Clinical Medicine, Zhejiang University of Chinese Medicine, Hangzhou, Zhejiang 310053, China., Department of Urology, The Second Hospital Affiliated to Zhejiang University of Chinese Medicine, Hangzhou, Zhejiang 310005, China.