Potentialities of MicroRNA Diagnosis in Patients with Bladder Cancer

Despite promising vista of the use of microRNA in molecular diagnosis of bladder cancer, there are few data on their expression profiles, which impedes assessment of diagnostic value of these marker molecules. In this study, suppression subtractive hybridization, on-chip hybridization, and high-throughput deep sequencing focused on profiling microRNA and assessing the diagnostic value of revealed marker molecules.

Bulletin of experimental biology and medicine. 2017 Nov 09 [Epub ahead of print]

P V Shegay, A A Zhavoronkov, N M Gaifullin, N V Vorob'ev, B Ya Alekseev, S V Popov, A V Garazha, A A Buzdin, A D Kaprin

National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia. ., First Oncology Research and Advisory Center (FORAC), Moscow, Russia., M. V. Lomonosov Moscow State University, Moscow, Russia., National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia.