Diuretic (18)F-Fluorodeoxyglucose PET/Computed Tomography in Evaluation of Genitourinary Malignancies

The interpretation of fluorodeoxyglucose (FDG) PET/computed tomography (CT) is often challenging for pelvic pathologies because of the physiologic bowel and urinary tract activity. Intense radiotracer activity in urinary tract interferes in image interpretation and leads to false-negative results in diagnosis and detection of local recurrence and regional lymph node metastases.

It is imperative to minimize unnecessary urinary bladder activity to improve the diagnostic yield of PET/CT. All the techniques described in the literature have their pros and cons. This article discusses FDG PET/CT in evaluation of urinary bladder cancer, cervical cancer, and ovarian cancer.

PET clinics. 2015 Sep 05 [Epub]

Krishan Kant Agarwal, Shambo Guha Roy, Rakesh Kumar

Diagnostic Nuclear Medicine Division, Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India. , Diagnostic Nuclear Medicine Division, Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India. , Diagnostic Nuclear Medicine Division, Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India. 

PubMed