Department of Chemical and Material Engineering, National Yulin University of Science and Technology, Taiwan.
Human urine contains a large number of proteins and peptides (the urinary proteome). Global analysis of the human urinary proteome is important for understanding urinary tract diseases. Bladder cancer is the most common urological cancer with higher incidence rates in endemic areas of Blackfoot disease (BFD) in southern Taiwan. The aim of this study was to use the proteomic approach to establish urinary protein biomarkers of bladder cancer. ADAM28, identified by proteomic approaches and confirmed by Western blotting, showed significant differences compared with normal individuals, so it may be a biomarker of bladder cancer.
Written by:
Yang MH, Chu PY, Chen SC, Chung TW, Chen WC, Tan LB, Kan WC, Wang HY, Su SB, Tyan YC. Are you the author?
Reference: Biochem Biophys Res Commun. 2011 Aug 12;411(4):714-20.
doi: 10.1016/j.bbrc.2011.07.010
PubMed Abstract
PMID: 21782798
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