A total of 1,182 patients with asymptomatic hematuria underwent voided cytology, upper tract imaging and cystoscopy. Also, clinical parameters such as age, gender, smoking status, and degree of hematuria were documented. From these parameters a nomogram was developed and internally validated using 200 bootstrap samples. Bladder cancer was present in 20.4% of patients. All parameters except gender were independent risk factors on multivariate analysis. The odds ratios for increasing age, smoking status, gross hematuria and positive cytology were 1.03, 3.72, 1.71, and 14.71. The accuracy of the nomogram for the prediction of present bladder cancer was as high as 83.5%. The authors concluded that the presence of bladder cancer can be predicted with high accuracy.
This trial provides a practical approach to predict the presence of bladder cancer using well-known parameters.
Presented by Shahrokh Shariat, MD, PhD, et al. at the 26th Annual European Association of Urology (EAU) Congress - March 18 - 21, 2011 - Austria Centre Vienna, Vienna, Austria
Reported for UroToday by Christian Doehn, MD, PhD, Department of Urology, University of Lübeck Medical School, Lübeck Germany.
View EAU 2011 Annual Meeting Coverage
