Introduction: The aim of this study was to evaluate consistency between clinical lymph node positivity and pathological lymph node positivity in patients undergoing open radical cystectomy and pelvic lymph node dissection due to bladder cancer. Material and method: A total of 135 patients who had open radical cystectomy, extended lymph node dissection, and clear preoperative contrast-enhanced abdominopelvic computed tomography (CT) or magnetic resonance imaging (MRI) images were included in the study. Positive clinical lymph nodes and positive pathological lymph nodeswere recorded. The largest positive clinical and pathological lymph nodeswere recorded. In terms of clinical lymph node involvement, compatibility between radiological findings and pathological results was evaluated.Results: In the CT group, the sensitivity was 25.81%, specificity was 95.45%, positive predictive value (PPV) was 66.67%, negative predictive value (NPV) was 78.50%, and accuracy was 77.31%. In the MRI group, the sensitivity was 50.00%, specificity was 100%, PPV was 100%, NPV was 76.92%, and accuracy was 81.25%. For consistency between pathological lymph nodes and clinical lymph nodes according to the imaging type, there was no statistically significant difference in the sensitivity, specificity, NPV, and accuracy rates between the imaging techniques (p > 0.05). However, the PPV was significantly higher in the MRI group than the CT group (100% vs.66.67%, respectively; p = 0.014).Conclusion: Positive lymph nodes play a critical role in the prognosis of patients with bladder cancer and the sensitivity of contrast-enhanced abdominopelvic CT and MRI used routinely in clinical practice is low in lymph node detection. MRI seems more reliable than CT in lymph node detection.
The aging male : the official journal of the International Society for the Study of the Aging Male. 2020 May 13 [Epub ahead of print]
Musab Ali Kutluhan, Emrah Özsoy, Fulya Başkak, Ahmet Ürkmez, Ramazan Topaktaş, Orhan Koca
Department of Urology, Istanbul, Health Sciences University, Fatih Sultan Mehmet Training and Research Hospital, Turkey., Department of Urology, Health Sciences University, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey., Department of Radiology, Health Sciences University, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey., Medistate Private Hospital, Istanbul, Turkey.