Trimodality bladder preservation (BP) is an accepted alternative to radical cystectomy for patients with muscle invasive bladder cancer (MIBC). The global utilization of BP is variable, and practice patterns have not been previously studied in Russia. We sought to elucidate the contemporary BP practice patterns in Russia and determine the impact of the BP workshop on attitudes of Russian radiation oncologists (ROs) towards BP. The workshop was focused on patient workup, selection for BP, chemotherapy choices, radiation therapy (RT) contouring and planning, patient counseling. A total of 77 pre- and 32 matched post-workshop IRB-approved surveys, based on the workshop content, were analyzed using descriptive statistics to determine baseline clinical experience and patterns of care. The impact was judged by changes in participants' responses. A total of 56% of respondents had experience with delivering bladder-directed RT, and 60% of those treated both operable and inoperable MIBC patients. Only 10% felt uncomfortable offering an operable patient BP modality. Prior to the workshop, almost half of respondents estimated universal poor bladder (44%) and erectile functions (47%) after BP. The workshop resulted in dramatic change in participants' attitudes towards long-term urinary (Stuart-Maxwell test, p < 0.01) and sexual (exact McNemar test, p < 0.01) side effects. Prior to the workshop, only 47% of respondents routinely discussed smoking cessation (SC) with their patients, whereas after workshop, 88% agreed that SC discussion is mandatory (exact McNemar test, p = 0.04). BP for MIBC is commonly used in Russia. Our workshop resulted in dramatically improved understanding of long-term BP toxicities and inspired Russian ROs to incorporate SC counseling into routine clinical management.
Journal of cancer education : the official journal of the American Association for Cancer Education. 2020 Mar 04 [Epub ahead of print]
Timur Mitin, Natalia Dengina, Marina Chernykh, Sergey Usychkin, Oleg Gladkov, Catherine Degnin, Yiyi Chen, Dmitry Nosov, Ilya Tsimafeyeu, Charles R Thomas, Sergei Tjulandin
Department of Radiation Medicine, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. ., Department of Radiotherapy, Ulyanovsk Regional Cancer Center, Ulyanovsk, Ulyanovsk oblast, Russia., PET-Technology Podolsk, Podolsk, Russia., Medscan Clinic, Moscow, Russia., Evimed Medical Center, Chelyabinsk, Russia., Biostatistics Shared Resources, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Department of Radiation Medicine, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA., The Central Clinical Hospital of the Presidential Administration of the Russian Federation, Moscow, Russia., Kidney Cancer Research Bureau, Moscow, Russia., N.N. Blokhin Russian Cancer Center, Moscow, Russia.