Aggressive treatment for urothelial cancer-complete urinary tract extirpation: Operative feasibility in two cases.

Bladder cancer (BC), the most common malignancy of the urinary tract, accounts for 90-95% of all urothelial carcinomas (UCs), while upper urinary tract UC (UUTUC) accounts for only 5-10%. Radical nephroureterectomy with excision of bladder cuff, and radical cystectomy with pelvic lymph node dissection and a urinary diversion (UD) are the gold standard treatments for UUTUC and muscle-invasive bladder cancer (MIBC), respectively. These two treatments can be performed simultaneously when a bilateral or unilateral UUTUC is present with a MIBC, and are called complete urinary tract extirpation (CUTE) and hemi-CUTE, respectively. This complex surgery can help the patient by avoiding multi-staged surgeries, repeated anesthesia, and delay in completion of treatment. Herein, we report the first cases of a hemi-CUTE and CUTE in our department and share our experience with this aggressive and complex surgical treatment.

Turkish journal of urology. 2018 Dec 21*** epublish ***

Murat Akand, Özcan Kılıç, İsmail Harmankaya, Pınar Karabağlı, Çağdaş Yavaş, Özlem Ata

Department of Urology, Selçuk University School of Medicine, Konya, Turkey., Department of Pathology, Selçuk University School of Medicine, Konya, Turkey., Department of Radiation Oncology, Selçuk University School of Medicine, Konya, Turkey., Department of Medical Oncology, Selçuk University School of Medicine, Konya, Turkey.