Bladder cancer presenting with acrometastases: a different cause of foot pain

Acrometastasis means tumor seeding distally to the elbow or the knee and is an uncommon event. Foot acrometastases occur in 0.58% of patients with skeletal metastases overall, and only about 10% of these are caused by bladder cancer. We present a case of bladder cancer manifesting with insidious foot pain, caused by multiple lytic lesions located solely at the left foot. It was suspected after whole-body CT and later confirmed by biopsy result. We enumerate the differential diagnosis of distal extremity lytic lesions for educational purposes and review the literature listing similar published cases.

Skeletal radiology. 2018 Feb 01 [Epub ahead of print]

João Matos, Ilaria Mussetto, Raffaella Podestà, Daria Schettini, Nicoletta Gandolfo

Dipartimento di Scienze della Salute, Universita degli Studi di Genova, Via Antonio Pastore, 1, 16132, Genoa, Italy. ., Dipartimento di Scienze della Salute, Universita degli Studi di Genova, Via Antonio Pastore, 1, 16132, Genoa, Italy., Department of Radiology, Ospedale Villa Scassi - Sampierdarena, Corso Scassi 1, 16121, Genoa, Italy.