Bladder Herpes Infection in a Patient with Low-Grade Non-Muscle-Invasive Bladder Cancer

Bladder herpes is a very uncommon event related to herpes simplex virus infection. We report a 69-year-old man with 4-year history of bladder cancer who presented with presented with dysuria and urinary frequency. Cystoscopy showed erythematous lesion of the bladder mucosa that was biopsied and revealed multi-lobed nuclei with eosinophilic intranuclear inclusions, and presence of intracytoplasmic vacuoles that were suggestive of bladder involvement by herpes simplex virus (HSV). Different bladder disorders have been associated to herpes virus, but spontaneous resolution generally occurs in 1 to 2 months.

Urology. 2017 Nov 13 [Epub ahead of print]

Pablo Garrido-Abad, Ariel Díaz-Menéndez, Manuel Fernández-Arjona

Urology Department, Hospital Universitario del Henares, Avda Marie Curie s.n 28822. Coslada. Madrid. Spain. Electronic address: ., MD. Pathology Department. Hospital Universitario del Henares., PhD. Urology Department. Hospital Universitario del Henares.