Ventral-Onlay Buccal Mucosa Graft Substitution Urethroplasty for Urethral Stricture in Females

To present our outcomes of ventral-onlay buccal mucosa graft substitution urethroplasty (VOBMGSU) in treating female urethral stricture (FUS).

A review of a prospectively collected database of 22 consecutive women (median age 50 years, range 34-72) with urethral stricture having VOBMGSU since June 2012 and a minimum follow up of 6 months (median 21. 5, range 6-51). Data was analysed for stricture recurrence, change in median peak free flow rate (Qmax) and median post-void residuals (PVR). Statistical analysis was performed with the Wilcoxon signed rank test, Students T Test and Mann-Whitney U Test.

Freedom from stricture recurrence was achieved in 21/22 (95.5%) women. Median Qmax significantly improved from 7 ml/s (range 3.5-11) to 18 ml/s (range 5-37) (p < 0.05). Median PVR significantly reduced from 100mls (range 0-300) to 15 mls (range 0-150) (p < 0.05). Short and longer-term complication rates were low. One patient developed mild de novo stress urinary incontinence, which settled with conservative measures by 6 months.

Early and medium term results indicate that VOBMGSU is an excellent treatment for female urethral stricture that can avoid the need for repeat procedures regularly required after traditional endoscopic management. This article is protected by copyright. All rights reserved.

BJU international. 2017 Jul 27 [Epub ahead of print]

Bashir M B Mukhtar, Marco Spilotros, Sachin Malde, Tamsin J Greenwell

University College London Hospital, Department of Urology, UCLH, Westmoreland Street, 16-18 Westmoreland Street Hospital, London, W1G 8PH, UK.