Underactive bladder (UAB) is considered the symptom complex associated with the urodynamic diagnosis of detrusor underactivity.
The aim of this research was to investigate the patient reported experience of the symptoms, signs, and impact of UAB. This research is also part of the initial qualitative phase for the development of a new patient reported outcome measure for the assessment of UAB.
Qualitative methods were used to understand the experience of UAB from a patient perspective, in a purposive sample of male (n=29) and female (n=15) patients aged 27-88 yr (mean: 64 yr), diagnosed with a primary diagnosis of detrusor underactivity, with or without coexisting urological conditions. Semistructured interviews were conducted in Bristol, UK.
Male and female patients reported a variety of lower urinary tract symptoms and associated impact on quality of life. Storage symptoms of nocturia, increased daytime frequency, and urgency, and the voiding symptoms of slow stream, hesitancy, and straining were reported by over half of the patients. A sensation of incomplete emptying and postmicturition dribble were also frequently described. Most had a post void residual >30ml (n=34, 77%, median: 199ml) with many reporting urinary tract infections, a history of self-catheterisation, and some experiencing occasional acute retention episodes. These symptoms and signs can have a broad impact on quality of life including having to plan their daily activities around the location of toilets, disruption to sleep, social life, and associated effect on family and friends.
Knowledge of the lived experience of UAB obtained in the current study will be used for the development of a new patient reported outcome measure and help inform the current working definition of UAB.
The symptoms, signs, and impact on quality of life of underactive bladder are described by patients with the condition.
European urology. 2017 Apr 08 [Epub ahead of print]
Alan D Uren, Nikki Cotterill, Christopher Harding, Christopher Hillary, Christopher Chapple, Monique Klaver, Dominique Bongaerts, Zalmai Hakimi, Paul Abrams
Department of Urology, Bristol Urological Institute, Bristol, UK. Electronic address: ., Department of Urology, Bristol Urological Institute, Bristol, UK., Department of Urology, Freeman Hospital, Newcastle, UK., Department of Urology, Royal Hallamshire Hospital, Sheffield, UK., Astellas Pharma B.V., Leiden, The Netherlands.