[Pregnancy and delivery for women with congenital spinal cord defects and neurogenic bladder]

Data are scarce regarding pregnancy and delivery among women with a neurogenic bladder due to congenital spinal cord defects.

To report the obstetrical and urological outcomes of women with congenital spinal cord defects and vesico-sphincteric disorders.

A retrospective multicentric study included all consecutive women with a neurogenic bladder due to congenital spinal defects, who delivered between January 2005 and December 2014. The following data were collected: demographics, neuro-urological disease characteristics, urological and obstetrical history, complications during pregnancy, neonatal outcomes, and changes in urological symptoms.

Overall, sixteen women, median age 29,4 years old (IQR 22-36), had a total of 20 pregnancies and 21 births (15 caesareans, 5 vaginal deliveries). Prior to the beginning of their first pregnancy, 12 patients were under intermittent self-catheterization. Symptomatic urinary tract infections during pregnancy occurred in 11 pregnancies, including 4 pyelonephritis. In 4 women, stress urinary incontinence had worsened but recovered post-partum. In 3 women, de novo clean intermittent catheterization became necessary and had to be continued post-partum. During 3 pregnancies, anticholinergic treatment had been started or increased because of urge urinary incontinence worsened. These changes were maintained after delivery. The median gestational age at birth was 39.0 weeks (IQR 37.8-39.5). There were 15 caesarean sections, of which 9 were indicated to prevent a potential aggravation of vesico-sphincteric disorders. Among the 5 pregnancies with vaginal delivery, there was no post-partum alteration of the sphincter function.

Successful pregnancy outcome is possible in women with congenital spinal cord defects and vesico-sphincteric disorders but it requires managing an increased risk of urinary tract infections, caesarean section, and occasionally worsened urinary incontinence.

5.

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2017 Jun 16 [Epub ahead of print]

Q Manach, M Dommergues, P Denys, K Loiseau, B Idiard-Chamois, E Chartier-Kastler, V Phé

Service d'urologie, faculté de médecine Pierre-et-Marie-Curie, Sorbonne universités, université Paris 6, hôpital universitaire Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. Electronic address: ., Service de gynécologie obstétrique, faculté de médecine Pierre-et-Marie-Curie, Sorbonne universités, université Paris 6, hôpital universitaire Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. Electronic address: ., Service de médecine physique et rééducation, université de Saint-Quentin-en-Yvelines, hôpital Raymond-Poincaré, Assistance publique-Hôpitaux de Paris, 104, boulevard Raymond-Poincaré, 92380 Garches, France. Electronic address: ., Service de médecine physique et de réadaptation, faculté de médecine Pierre-et-Marie-Curie, université Paris 6, hôpital universitaire Rothschild, Assistance publique-Hôpitaux de Paris, 5, rue Santerre, 75012 Paris, France. Electronic address: ., Service de gynécologie obstétrique, hôpital institut mutualiste Montsouris, 42, boulevard Jourdan, 75674 Paris cedex 14, France. Electronic address: ., Service d'urologie, faculté de médecine Pierre-et-Marie-Curie, Sorbonne universités, université Paris 6, hôpital universitaire Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. Electronic address: ., Service d'urologie, faculté de médecine Pierre-et-Marie-Curie, Sorbonne universités, université Paris 6, hôpital universitaire Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. Electronic address: .

Pelvic Health Weekly Newsletter