Urethral bulking for recurrent stress urinary incontinence after midurethral sling failure

AIMS - To assess the effectiveness of a polyacrylamide hydrogel (PAHG; Bulkamid®) in treating recurrent stress urinary incontinence (SUI) following a previous midurethral sling (MUS) implant.

METHODS - This observational study, conducted since 2009, included 60 patients with recurrent SUI or mixed urinary incontinence (MUI) after a previous MUS and who chose to be treated with PAHG.

Objective and subjective outcomes were assessed at 1, 6, and 12 months after the initial injection. Patients were classified as cured based on a negative cough test (supine and standing) and 50% compared with preoperative urine loss and a VAS score improved by ≥75%.

RESULTS - The volume of PAHG injected in the current study ranged from 1-3 ml. Cured/improved rates were 93.3% (56/60), 88.3% (53/60), and 83.6% (46/55) at 1, 6, and 12 months, respectively. Patients with MUI had a cured urgency urinary incontinence rate of 36.8%, 47.4%, and 38.9%, respectively. Voiding dysfunction rates were 13.3% (8/60), 8.3% (5/60), and 1.8% (1/55) at 1, 6, and 12 months and urinary tract infection rates were 5% (3/60), 11.7% (7/60), and 3.6% (2/55), respectively. Other adverse events were short-term and/or observed in <4% of patients.

CONCLUSIONS - PAHG can be used to treat recurrent SUI after MUS failure with good outcome and low complication rates. Neurourol. Urodynam. © 2016 Wiley Periodicals, Inc.

Neurourology and urodynamics. 2016 Mar 31 [Epub ahead of print]

Irena Zivanovic, Oliver Rautenberg, Kurt Lobodasch, Günther von Bünau, Claudia Walser, Volker Viereck

Department of Gynecology and Obstetrics, Cantonal Hospital, Frauenfeld, Switzerland., Department of Gynecology and Obstetrics, Cantonal Hospital, Frauenfeld, Switzerland., Department of Gynecology, German Red Cross Hospital Chemnitz-Rabenstein, Chemnitz, Germany., Coombe Women and Infants University Hospital, Dublin, Ireland., Department of Gynecology and Obstetrics, Cantonal Hospital, Frauenfeld, Switzerland., Department of Gynecology and Obstetrics, Cantonal Hospital, Frauenfeld, Switzerland.

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