The impact of overweight in the efficiency and complications of midurethral sling in patients with stress urinary incontinence: a systematic review and meta-analysis

To compare the efficiency and complications of normal weight and overweight women with stress urinary incontinence (SUI) after surgery.

We searched the PubMed, Embase, and Cochrane Library Databases to identify all compared results, including those involving the terms normal weight, overweight, body mass index (BMI), and SUI. After treatment with surgery, the efficiency (subjective cure rate, objective cure rate, UDI-6, and IIQ-7) and complications were compared between the normal weight and overweight groups.

The study inclusion criteria were met by 20 studies involving 3829 patients. The data synthesized from these studies indicated that the subjective and objective cure rates in the normal weight group were significantly more effective than those in the overweight group (RR 1.07; 95% CI 1.04-1.10; P < 0.00001; RR 1.24; 95% CI 1.18-1.30; P < 0.00001), while the IIQ-7 and UDI-6 were no different between the two groups (MD 0.07; 95% CI - 1.44 to 1.58; P = 0.93; MD 0.18; 95% CI - 1.24 to 1.60; P = 0.81). For the data of complications, only the urgency was more in the overweight group (RR 0.68, 95% CI 0.55-0.84, P = 0.0003).

The objective success rate and subjective success rate of the surgery were higher in normal weight patients than those in overweight patients. Also, the side effects between the two groups were not significantly different.

International urology and nephrology. 2018 Jul 14 [Epub ahead of print]

Yi Sun, Guo-Lin Lei, Cai Tang, Lu Yang, Hong Shen, Qiang Wei

Department of Urology, West China Hospital of Sichuan University, No.37 Guoxue Xiang, Chengdu, 610041, Sichuan, China., Department of Urology, People's Hospital of Jianyang City, Yiyuan Road, Jianyang, Sichuan, China., Department of Urology, West China Hospital of Sichuan University, No.37 Guoxue Xiang, Chengdu, 610041, Sichuan, China. .

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