ProACT in the management of stress urinary incontinence after radical prostatectomy. What happens after 8 years of follow up? monocentric analysis in 42 patients.

Stress urinary incontinence is defined by a complaint of any involuntary loss of urine on effort or physical exertion or on sneezing or coughing and represents a major complication after radical prostatectomy. According to surgical technique, incidence of post-prostatectomy incontinence varies from open (7-39.5%), laparoscopic (5-33.3%) or robotic-assisted (4-31%) approaches. The ProACT® device (Uromedica, Inc., MN) is a possible surgical option for the treatment of this condition.

We retrospectively analyzed surgical records of consecutive patients underwent ProACT® implantation in our department between January 2006 to November 2010. We collected data at 6 and 12 months after surgical approach about the daily pad use, International Prostatic Symptoms Score and its quality of life domain.

42 patients were included in the final analysis. Most patients (92.9%) received minimally invasive surgery for treating prostate cancer. During the follow up after 6 and 12 months, the daily pad, International Prostatic Symptom Score and its quality of life domain significantly improved compared to preoperative outcomes. The logistic regression analysis found that presence of comorbidities was the only predictive factor of low satisfaction rate (PGE-I > 2) in patients who underwent ProACT® implant.

ProACT® implant represents an effective and safe treatment for post-prostatectomy stress urinary incontinence with a high satisfaction degree and a low rate of complications.

Journal of basic and clinical physiology and pharmacology. 2022 Apr 07 [Epub ahead of print]

Maida Bada, Felice Crocetto, Biagio Barone, Davide Arcaniolo, Sebastiano Rapisarda, Antonio Aliberti, Guglielmo Zeccolini, Antonio Celia

Department of Urology, Hospital "San Bassiano", Via dei Lotti 40, 36061, Bassano del Grappa (VI), Italy., Department of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples "Federico II", Via Sergio Pansini 5, 80131, Napoli (NA), Italy., Department of Urology, Hospital "Pederzoli", Via Monte Baldo 24, 37019, Peschiera del Garda (VR), Italy., Department of Urology, Hospital "San Leonardo", ASL Napoli 3 Sud, Via Salvador Allende 68, 80053, Castellammare di Stabia (NA), Italy.

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