Real-life patient experiences of TTNS in the treatment of overactive bladder syndrome.

Overactive bladder syndrome (OAB) is defined as urinary urgency, with or without urgent urinary incontinence; it is often associated with urinary frequency and nocturia, in the absence of any pathological or metabolic conditions that may cause or mimic OAB. The aim of this study was to evaluate the long-term real-life adherence of transcutaneous tibial nerve stimulation (TTNS) in the treatment of OAB, patient satisfaction of the treatment, and reasons for quitting therapy.

In this single center study, all patients who had a positive effect on percutaneous tibial nerve stimulation (PTNS) and continued to receive home-based treatment with TTNS since 2012 were included for analysis. Patients were retrospectively asked to fill out a questionnaire regarding satisfaction, reasons for quitting, and additional or next line of therapy.

We included 42 patients for this study, 81% of these patients were female (n = 34). The median age was 67 years (range 36-86). Most of the patients (64%, n = 27) were diagnosed with OAB wet. The median TTNS treatment persistence was 16 months (range 1-112 months). Reasons and percentages for stopping therapy were: 55% stopped treatment due to loss of effect, and 24% stopped because of preferring other type of neuromodulation. The mean satisfaction score (scale 1-10) in patients who continued TTNS was 6.2 (n = 9, SD 1.30) versus 5.4 (n = 29, SD 2.24) for patients who quit therapy. We did not find a statistically significant difference between the two groups (p = 0.174).

TTNS, although effective in the short-term, is not effective in the long-term. In combination with a low satisfaction rate among patients, there is a need for improvement in terms of OAB treatment modalities.

Therapeutic advances in urology. 2021 Aug 31*** epublish ***

Manon Te Dorsthorst, Michael van Balken, Dick Janssen, John Heesakkers, Frank Martens

Radboudumc, Geert Grooteplein Zuid 10, Nijmegen, 6500 HB, Netherlands., Rijnstate, Arnhem, Gelderland, Netherlands., Radboudumc, Nijmegen, Netherlands., Maastricht University Medical Centre, Maastricht, Netherlands.

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