Linkage of lower urinary tract symptoms to sleep quality in elderly men with nocturia: a community-based study using home-measured electroencephalogram data

The aim of the present study is to objectively investigate the relationship between sleep quality/efficiency and factors associated with micturition using at-home EEG assessment.

Participants were recruited from among those enrolled in the Fujiwara-kyo Study, a community-based longitudinal evaluation that began in Nara Prefecture, Japan, in 2007. Included participants were men at least 65 years of age who woke up in the middle of the night/early morning at least three times per week with the urge to void. We evaluated lower urinary tract symptoms using the International Prostate Symptoms Score (IPSS) and subjective sleep quality using the Pittsburgh Sleep Quality Index (PSQI). Uroflowmetry and 3-day frequency volume charting measurements were also obtained. EEG recordings were obtained during sleep to evaluate objective sleep quality.

Final analysis included data from 47 participants. IPSS-QOL scores and slow wave sleep time were independent predictors of good subjective sleep quality, as determined by PSQI scores. Nocturnal urinary volume was an independent predictor of greater sleep efficiency. Qmax was an independent predictor of longer slow wave sleep time.

In elderly men with nocturia, sleep quality is associated with lower urinary tract function. Higher subjective sleep quality is associated with longer slow wave sleep time and less severe LUTS. Higher objective sleep quality is further associated with higher urinary flow rate and lower nocturnal urinary volume.

The Journal of urology. 2016 Aug 06 [Epub ahead of print]

Chie Matsushita, Kazumasa Torimoto, Daisuke Goto, Yosuke Morizawa, Keisuke Kiba, Masatake Shinohara, Akihide Hirayama, Norio Kurumatani, Kiyohide Fujimoto

Department of Urology, Nara Medical University, Kashihara, Nara, Japan., Department of Urology, Kindai University Nara Hospital, Ikoma, Nara, Japan., Department of Community Health and Epidemiology, Nara Medical University, Kashihara, Nara, Japan.