It is well established that sleep disorders (SDs) are associated with the prevalence of nocturia in men. While previous literature supports that patients with SDs are at increased risk of nocturia, the risk of daytime lower urinary tract symptoms (LUTS) has not been well established.
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We examined the National Health and Nutrition Examination Survey (NHANES) database between 2006-2008. Men over the age of 40 who completed the sleep, prostate and kidney questionnaires were included in the study. LUTS was defined as having two more of the following symptoms: hesitancy, incomplete emptying, or nocturia (≥2). Multivariable models using logistic regressions were used to compare groups of men with and without a SD.
Of the 3071 men who completed all of the survey questions, 270 (8.8%) men reported a SD. Men with SDs had a significantly higher BMI (30.8 vs. 27.4, p <0.01), likelihood of reporting diabetes (20.3% vs. 10.2%, p<0.01) and more co-morbidities (72.6% vs. 45.2%, p<0.01) compared to men without SD. Multivariable logistic regressions demonstrated that men with SD were more likely to report nocturia (OR 1.23, p<0.01), LUTS ≥2 (OR 1.12, p < 0.01), and daytime LUTS (OR 1.27, p<0.01).
Independent of BMI, diabetes and increased number of co-morbidities, SDs are associated with an increased risk of both nocturia and daytime LUTS. Based upon the present data; clinicians should consider assessing LUTS in men with SDs as intervention could improve both nighttime and daytime urinary symptoms.
The Journal of urology. 2018 Feb 02 [Epub ahead of print]
Richard J Fantus, Vignesh T Packiam, Chi H Wang, Bradley A Erickson, Brian T Helfand
Section of Urology, Department of Surgery, University of Chicago Medicine, Chicago, IL., NorthShore University Health System, Evanston, IL., University of Iowa, Department of Urology, Iowa City, IA.