Kenalog Injection into Hunner's Lesions as a Treatment for Interstitial Cystitis/Bladder Pain Syndrome

This study aims to evaluate the effectiveness of kenalog injection into Hunner's lesions.

All patients had cystoscopy and bladder hydrodistention with corticosteroid injection into Hunner's lesions over a 2. 5-year period. Data include patient characteristics and pre- and post-operative validated questionnaires. Spearman Correlation and Wilcoxon t-tests were used for analysis.

One hundred patients were reviewed retrospectively. There was a 1.1 point decrease in pain at 12 weeks post-operation (p = 0.435). Urinary frequency decreased from a mean of 11.7 to 9.1 daily episodes (p = 0.05), and nocturia from a mean of 3 to 1.6 nightly episodes (p = 0.008).

The use of a corticosteroid may be beneficial to symptom control and improvement in the quality of life of interstitial cystitis/painful bladder syndrome patients. Patients had improved frequency and nocturia 12 weeks post injection.

Current urology. 2017 Jul 30 [Epub]

Lauren Rittenberg, Darlene Morrissey, Dominique El-Khawand, Kristene Whitmore

Division of Female Pelvic Medicine and Reconstruction, Drexel University College of Medicine, Philadephia, Pennsylvania, USA.