[Interstitial cystitis : Diagnosis and pharmacological and surgical therapy]

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic debilitating condition which generally has a severely negative impact on quality of life. An autoimmune genetic predisposition correlates with the theory of pathogenesis. Diagnosis requires history, diaries, physical examination, exclusion of other diseases, cystoscopy with or without hydrodistension and/or bladder biopsy. Novel biological markers are upcoming but not established. Behavioural, pharmacological oral and intravesical, interventional and surgical therapies with a wide range of reported success are available. A multimodal approach is recommended, although most of the therapeutic options lack a high degree of evidence.

Der Urologe. Ausg. A. 2017 May 24 [Epub ahead of print]

A Gonsior, J Neuhaus, L C Horn, T Bschleipfer, J-U Stolzenburg

Klinik für Urologie, Universitätsklinik Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland. ., Klinik für Urologie, Universitätsklinik Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland., Institut für Pathologie, Universitätsklinik Leipzig AöR, Liebigstraße 26, 04103, Leipzig, Deutschland., Klinik für Urologie, Klinikum Weiden, Söllnerstraße 16, 92637, Weiden, Deutschland.