Transurethral Resection Alone Versus Resection Combined with Therapeutic Hydrodistention as Treatment for Ulcerative Interstitial Cystitis: Initial Experience with Propensity Score Matching Studies

We compared the therapeutic efficacy of transurethral resection (TUR) alone to that of TUR combined with therapeutic hydrodistention in patients with ulcerative interstitial cystitis (IC).

The study subjects were newly diagnosed IC patients 44 female patients who underwent TUR to treat ulcerative IC and who were available for follow-up, without recurrence of disease for 12 months. We retrospectively studied both patients who underwent TUR alone (Group I) and those who underwent TUR combined with therapeutic hydrodistention (Group II). Improvements in pain and voiding symptoms were retrospectively evaluated using a 10-point visual analog pain scale (VAS) and a 3-day micturition chart.

Group I included 22 patients and Group II 22 patients of mean ages 58.45 ± 11.01 and 56.27 ± 11.86 years, respectively. Use of a 10-point VAS showed that pain decreased after the procedures in both groups, but the improvement did not differ between groups. The maximum functional bladder capacities (FBCs) of Group I patients were 161.36, 192.47, and 204.12 mL, respectively, before, and at 6 and 12 months after the operation; the figures for Group II were 175.45, 263.14, and 291.17 mL, respectively. The voiding frequencies of Group I were 12.59, 10.67, and 9.89 times daily, respectively, before, and at 6 and 12 months after the operation; the figures for Group II were 12.95, 9.5, and 8.29 times daily, respectively.

TUR combined with therapeutic hydrodistention increased bladder capacity and improved voiding symptoms more so than did TUR alone for ulcerative interstitial cystitis.

Urology. 2016 Oct 05 [Epub ahead of print]

Sang Wook Lee, Woong Bin Kim, Kwang Woo Lee, Jun Mo Kim, Young Ho Kim, Bora Lee, Jae Heon Kim

Department of Urology, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea., Department of Urology, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea. Electronic address: ., Biostatistic consulting, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

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