Validation of a quality-of-life scale for women with bladder pain syndrome/interstitial cystitis - Abstract

Division of General Pediatrics, Children's Hospital Boston, Harvard Medical School, 21 Autumn Street, Boston, MA, 02215, USA.


To validate a disease-specific scale to measure the impact of symptoms of bladder pain syndrome/interstitial cystitis (BPS/IC), a condition that affects up to 6.5% of US women.

Participants were drawn from the RAND Interstitial Cystitis Epidemiology (RICE) Study, a telephone probability survey of 146,231 US households. Women who met RICE BPS/IC symptom criteria (n = 3,397) completed the 6-item RAND Bladder Symptom Impact scale (RICE BSI-6). The RICE BSI-6 was adapted from a scale used to assess the impact of diabetes on life and sexuality and modified based on expert input on face validity and focus group work; items specific to diabetic symptoms were eliminated. Validated scales of symptom severity, mental- and physical-health-related quality of life (QoL), depression, coping, and perceived control were used to assess convergent validity.

The RICE BSI-6 (α = 0.92) was significantly related to greater symptom severity, worse general mental- and physical-health-related QoL, more severe depression symptoms, and lower perceived control over life in general and over BPS/IC symptoms (P values < .05). It was also associated with less use of distancing coping (P < .05).

The RICE BSI-6 shows excellent internal consistency and strong convergent validity. It can be used to examine the effects of psychosocial and treatment interventions on QoL among women with BPS/IC.

Written by:
Bogart LM, Suttorp MJ, Elliott MN, Clemens JQ, Berry SH.   Are you the author?

Reference: Qual Life Res. 2011 Dec 7. Epub ahead of print.
doi: 10.1007/s11136-011-0085-3

PubMed Abstract
PMID: 22146841 IC/PBS/BPS/HBS Section


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