A systematic review of the cost of chronic pelvic pain in women.

To systematically summarize evidence on the costs related to chronic pelvic pain (CPP) for women.

Electronic databases (MEDLINE, EMBASE, PubMed, and Cochrane Library) were searched from 1990 up until January 2021, and limited to only English and French studies.

Of 1304 papers screened, 67 were screened in full-text, with a total of 13 studies included in final analysis. Studies focused on cost studies that estimated hospital cost or health system cost for pelvic pain, dysmenorrhea, dyspareunia, endometriosis with pain, interstitial cystitis or painful bladder syndrome were included.

A standardized data extraction form was created to extract study setting, design, and population, patient demographics, study duration, reported costs of chronic pelvic pain components and amounts. Two independent reviewers completed the data extraction and discrepancies were resolved through discussion with third reviewer available.

Estimated healthcare costs ranged from $1,367 to $7,043 per woman per year (USD). The prescription costs ranged from $193 to $2,457 per woman per year. Indirect costs ranged from $4,216 to $12,789 per woman per year. Combined costs ranged from $1,820 to $20,898 per woman per year. The yearly costs of CPP varied according to the country; yearly costs were estimated to be $2.8 billion/year, ¥191,680 to ¥246,488 per woman per year, and $16,970 to $20,898 per woman per year in the US, Japan, and Australia respectively. The literature suggests that chronic pelvic pain represents a considerable economic burden on women and healthcare systems internationally, with indirect costs contributing a significant portion of total costs.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC. 2021 Sep 26 [Epub ahead of print]

Ghi Huang, Ai-Lien Le, Yvette Goddard, Daniel James, Kednapa Thavorn, Magdalene Payne, Innie Chen

University of Ottawa, 75 Laurier Avenue East, Ottawa, Ontario, Canada, K1N 6N5., University of Ottawa, 75 Laurier Avenue East, Ottawa, Ontario, Canada, K1N 6N5; Ottawa Hospital Research Institute, 501 Smyth Rd, Ottawa, Ontario, Canada, K1H 8L6. Electronic address: ., The Ottawa Hospital, 501 Smyth Rd, Ottawa, Ontario, Canada, K1H 8L6., Ottawa Hospital Research Institute, 501 Smyth Rd, Ottawa, Ontario, Canada, K1H 8L6; School of Epidemiology and Public Health, Ottawa, Ontario, Canada, K1G 5Z3., University of Ottawa, 75 Laurier Avenue East, Ottawa, Ontario, Canada, K1N 6N5; Ottawa Hospital Research Institute, 501 Smyth Rd, Ottawa, Ontario, Canada, K1H 8L6; The Ottawa Hospital, 501 Smyth Rd, Ottawa, Ontario, Canada, K1H 8L6.

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