Interstitial Cystitis (IC) or Painful Bladder Syndrome (PBS) is a heterogeneous disease which pathogenetic mode development is not fully studied. In the presented literature review IC/PBS is considered as urothelial dysfunction. The main issues discussed relate to IC/PBS diagnosis and minimally invasive methods of its treatment including intravesical instillations of therapeutic agents, botulinum toxin injections into bladder wall and hydrodistension. Efficacy of the above therapeutic methods is far from the desired what gives rise to search novel minimally invasive technologies and protocols to improve the outcomes of traditional treatment methods.
Urologiia (Moscow, Russia : 1999). 2020 Nov [Epub]
A G Martov, N G Muzhetskaya, Y R Slyukova, R V Salyukov
Department of urology and Andrology of Federal Medical and Biological Center named after A.I. Burnazyan FMBA, Moscow, Russia.