Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating condition associated with intense pelvic pain and bladder storage symptoms. Since diagnosis is difficult, prevalence estimates vary with the methodology used. There is also a lack of proven imaging tools and biomarkers to assist in differentiation of IC/BPS from other urinary disorders (overactive bladder, vulvodynia, endometriosis, and prostatitis). Current uncertainty regarding the etiology and pathology of IC/BPS ultimately impacts its timely and successful treatment, as well as hampers future drug development. This review will cover recent developments in imaging methods, such as magnetic resonance imaging, that advance the understanding of IC/BPS and guide drug development.
F1000Research. 2018 Nov 09*** epublish ***
Pradeep Tyagi, Chan-Hong Moon, Joseph Janicki, Jonathan Kaufman, Michael Chancellor, Naoki Yoshimura, Christopher Chermansky
Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, 15213, USA., Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, 15213, USA., Lipella, Pittsburgh, USA., Urology, OU- Beaumont school of medicine, Royal oak, USA.