To compare the data of score symptoms (ICPI, ICSI, PUF and SF-36), voiding diaries, urodynamic studies and cystoscopy under general anaesthesia according to the anatomical bladder capacity for patients with IC/BPS.
Single-centre descriptive observational epidemiological study based on retrospective review of 134 patients managed for IC/BPS between January 2010 and December 2016. Patients were stratified into two groups according to anatomical bladder capacity measured under general anaesthesia: ≤ 400 mL (n=40) and > 400 mL (n=94).
Patients with an anatomical bladder capacity less than 400 of mL presented significantly different results for voiding diary data: higher total frequency (p=0.0023) especially at night (p=0.0008), lower functional bladder capacity (p=0.0082) and lower maximum bladder capacity (p=0.0001); urodynamic data: earlier onset of painful urge during bladder filling (p=0.0002), lower maximum bladder filling capacity (p=0.0001) and lower compliance (p=0.0067); and the findings of cystoscopy under general anaesthesia: more Hunner's lesions (p=0.00013). These patients presented poorer PUF symptom scores (p=0.0176) but associated with better overall quality of life as assessed by SF-36 (p=0.0295).
The anatomical bladder capacity, measured under general anaesthesia, can be used objectively to define two distinct groups of patients with symptoms of interstitial cystitis/bladder pain syndrome.
Urology. 2018 Aug 28 [Epub ahead of print]
Charles Mazeaud, Jérôme Rigaud, Amélie Levesque, François-Xavier Madec, Quentin-Come LE Clerc, Maxime Wack, Loïc LE Normand, Thibault Riant, Marie-Aimée Perrouin-Verbe
Department of Urology, Nantes University Hospital, 1 place Alexis-Ricordeau, 44000 Nantes, France., Department of Urology, Nantes University Hospital, 1 place Alexis-Ricordeau, 44000 Nantes, France. Electronic address: ., Department of epidemiology and biostatistics, Nancy University Hospital, 29 avenue du Maréchal de Lattre de Tassigny, 54035 Nancy Cedex, France., Pain Unit, Le Confluent, Catherine de Sienne Center, 2 rue Eric Tabarly, 44000 Nantes, France.