Steroid-responsive IgG4-related disease with isolated prostatic involvement: An unusual presentation with elevated serum PSA

Autoimmune prostatitis is known to occur as a part of multisystem fibro-inflammatory disorder known as IgG4 related disease (IgG4 RD). The usual presentation is with symptoms of gastro-intestinal disease with prostatic involvement presenting as lower urinary tract symptoms.

The disease responds to corticosteroids. We report an asymptomatic young man who was diagnosed to have IgG4 related prostatitis on TRUS-guided prostate biopsy done for elevated serum PSA, in the absence of any other systemic involvement. The treatment with steroid resulted in normalization of S PSA levels.

Indian journal of urology : IJU : journal of the Urological Society of India. 0000 [Epub]

Vikas Jain, Praveen Kumar Pandey, Chhagan Bihari

Department of Renal Transplant and Urology, Institute of Liver and Biliary Sciences, New Delhi, India., Department of Renal Transplant and Urology, Institute of Liver and Biliary Sciences, New Delhi, India., Department of Pathology, Institute of Liver and Biliary Sciences, New Delhi, India.