OBJECTIVE: To review the role of α-blockers in various urological conditions such as benign prostatic hyperplasia, overactive bladder, chronic prostatitis, and erectile dysfunction and as expulsive treatment of distal ureteral stones.
MATERIAL AND METHODS: We reviewed the latest scientific evidence in all the fields mentioned above, performing a critical analysis.
CONCLUSION: α-blockers are now considered first-line treatment in lower urinary tract symptoms secondary to benign prostatic hyperplasia, but the indications go beyond, and are able to improve, alone or in combination with other drugs, the previously mentioned pathologies. The uroselective properties of some α-blockers make them a highly safe medication.
Hernández Fernández C, Brenes Bermúdez F, Moncada Iribarren I. Are you the author?
Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Reference: Med Clin (Barc). 2012 Dec 1;139(13):582-7.
Article in Spanish.