Granulomatous prostatitis (GP) is an unusual and benign inflammatory condition of the prostate, where autoimmunity has been recognized as a key factor in the pathogenesis of GP in a subset of patients.
Clinically, GP poses diagnostic challenges as it may strongly mimic prostate cancer from a clinical, biochemical and radiological point of view. The occurrence of GP in patients suffering from psoriasis, a systemic autoimmune disease, has never been investigated. We describe the case of GP in a patient with psoriatic arthritis presenting with an increased prostate specific antigen level, and evidence of a nodular lesion visualized by prostate multiparametric magnetic resonance imaging, which was highly suspicious for aggressive prostate cancer.
Future science OA. 2020 Jun 17*** epublish ***
Luigi De Luca, Felice Crocetto, Biagio Barone, Massimiliano Creta, Salvatore Pesce, Achille Aveta, Maria Raffaela Campanino, Ciro Imbimbo, Nicola Longo
Department of Neuroscience, Reproductive Sciences & Odontostomatology, University of Naples Federico II, Naples, Italy., Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.