CHICAGO, IL USA (UroToday) - The PD injectable treatment collagenase clostridium histolyticum is currently under investigation in two double-blind, placebo-controlled, phase III trials.
Of the 832 men enrolled in 64 sites throughout the U.S. and Australia in these two trials, 643 had a baseline deformity of 30-60ᵒ and 189 had a penile curvature (PC) deformity of 60-90ᵒ. The greater the degree of curvature, the more the patient is bothered by his condition, experiencing moderate to severe distress. Notably, half of the men with a lower degree of curvature (30-60ᵒ) were significantly bothered by PD.
This study suggests the degree of curvature is bothersome, but alone does not represent the full impact of the disease. The psycho-social component is important when managing patients with PD.
Presented by Larry I. Lipshultz, MD,* et al. at the annual World Meeting on Sexual Medicine (WMSM) - August 26 - 30, 2012 - Sheraton Chicago - Chicago, Illinois USA
* Baylor College of Medicine
Reported for UroToday by Karen Roberts, Medical Editor