Surgical Management of Peyronie's Disease With Co-Existent Erectile Dysfunction.

Surgical intervention in Peyronie's disease (PD) should ideally be delayed until the resolution of acute inflammatory phase.

The objective of this review was to highlight the results of penile prosthesis to correct refractory erectile dysfunction (ED) in patients with PD, and the secondary procedures that may be required to correct the penile curvature.

A systematic search on PubMed online database using Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations was done using the MeSH terms "Peyronie's disease" and "erectile dysfunction."

Success and satisfaction rates of various procedures.

The search yielded 324 language-specific (English and Spanish language) articles and 58 articles were retained for final review. The following variables were assessed in different studies: number of patients, types of secondary procedure to correct the curvature, satisfaction rates, and follow-up period.

The aim of the surgery in PD should be to achieve a functionally straight penis (<20 degree curvature) with good erection. Patients with refractory ED in PD are candidates for penile prosthesis. Secondary procedures, like manual modeling, plication, plaque incision, or excision grafting, may be required depending on the degree of penile curvature and penile length. In quest for the best graft, TachoSil graft seems to have gained popularity in Europe. Krishnappa P, Fernandez-Pascual E, Carballido J, et al. Surgical Management of Peyronie's Disease With Co-Existent Erectile Dysfunction. Sex Med 2019;XX:XXX-XXX.

Sexual medicine. 2019 Sep 17 [Epub ahead of print]

Pramod Krishnappa, Esau Fernandez-Pascual, Joaquin Carballido, Ignacio Moncada, Enrique Lledo-Garcia, Juan Ignacio Martinez-Salamanca

Department of Urology, NU Hospitals, Bangalore, India. Electronic address: ., Department of Urology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain., Department of Urology and Robotic Surgery, Hospital La Zarzuela, c/Pléyades, Madrid, Spain., Department of Urology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.