[Low-intensity extracorporeal shockwave therapy for Peyronie's disease: A preliminary study of 32 cases]

To investigate the clinical effect of low-intensity extracorporeal shockwave therapy (LI-ESWT) on Peyronie's disease.

From October 2016 to December 2017, we treated 32 cases of Peyronie's disease by LI-ESWT, with the therapeutic index of 0. 09 mJ/mm2 and a pulse frequency of 120 beats/min. Each plaque was approached from two angles, each angle with a shockwave output of 900 times, and the larger ones from three points, each with an output of 600 times in addition to 300 times from the distal and proximal ends of the plaque, respectively. All the patients received 12 courses of treatment (2 courses a week) with a break of 3 weeks between the 1st and 2nd 6 courses. Then we observed the plague size and penile curvature of the patients, obtained their scores on the Visual Analogue Scale (VAS) and International Index of Erectile Function 5 (IIEF-5), and recorded their adverse reactions.

The plagues were softened or diminished in different degrees in 9 of the 32 cases and erectile pain was alleviated in 15 cases after treatment. Penile curvature at erection, however, showed no significant improvement. The IIEF-5 scores were increased in 18 of the patients complicated with varied degrees of erectile dysfunction after LI-ESWT. No obvious complications were observed in any of the patients.

Low-intensity extracorporeal shockwave therapy has a certain effect on Peyronie's disease by relieving plague-induced pain and improving the patient's penile erection and quality of life.

目的: 探讨低能量体外冲击波治疗阴茎硬结症的临床效果。方法: 自2016年10月至2017年10月对32例阴茎硬结症患者应用低能量体外冲击波进行治疗,治疗参数为0.09 mJ/mm2、脉冲频率120次/分,每个硬结从两个角度治疗,每个角度冲击波输出900次,较大的硬结分3个点打,每点600次,另外再于硬结的远端及近端各打300次。每周治疗2个疗程,最初6个疗程连续进行,之后休息3周再治疗6个疗程。疗程结束后观察硬结大小、阴茎弯曲度、VAS评分、IIEF-5评分及不良反应等。结果: 在32例患者中,9例患者阴茎硬结不同程度的变软或变小;阴茎勃起疼痛的患者中,15例疼痛减轻;阴茎勃起后明显弯曲的患者治疗后改善不明显;合并不同程度勃起功能障碍患者中,18例IIEF-5评分有所提高;所有治疗患者均未见明显并发症。结论: 低能量体外冲击波可以缓解阴茎硬结症导致的疼痛,改善勃起功能,提高患者生活质量,对阴茎硬结症有一定的疗效。.

Zhonghua nan ke xue = National journal of andrology. 2018 Apr [Epub]

Peng-Cheng Li, Xin Chen, Xiao-Bo Zhu, Tao Shi, Fei Song, Hua-Wei Huang, Xiang-Sheng Zhang

Department of Andrology, Henan Provincial People's Hospital, Zhengzhou, Henan 450000, China.


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