Malleable Penile Implant Is an Effective Therapeutic Option in Men With Peyronie's Disease and Erectile Dysfunction

The inflatable penile prosthesis (IPP) is typically the preferred implant for Peyronie's disease (PD) and malleable penile prostheses (MPPs) have been discouraged.

To evaluate the effectiveness and patient satisfaction of the MPP vs IPP in patients with PD.

Men with PD and erectile dysfunction who elected for penile implant surgery constituted the study population. Preoperatively, demographic and comorbidity parameters were recorded. Curvature was measured with a goniometer at maximum rigidity after intracavernosal injection of a vasoactive agent. Postoperatively, overall satisfaction was measured at 3, 6, 12, and 24 months on 5-point Likert scale from 1 (dissatisfied) to 5 (very satisfied).

166 men with a mean age of 59 ± 10 years were analyzed. The mean preoperative curvature in the entire cohort was 65° (range = 30-130°). 94% of patients with MPP had total resolution of their curvature at the end of the operation, whereas 8 patients (6%) had residual curvature (25-40°). In the IPP group 25 of 30 (83.3%) had a straight penis at the end of surgery, whereas 5 of 30 (16.7%) had residual curvature, with the mean magnitude being 33° in the MPP group and 30° in the IPP group. 86% of all patients had diabetes. There were no differences between the 2 implant groups in age, hemoglobin A1c, body mass index, or smoking status. The mean patient satisfaction was 4.42 ± 0.70 (range = 2-5) and there was no difference between the 2 groups. The mean follow-up period was 23.4 months (range = 6-29 months).

We found that the MPP is as effective as the IPP in curvature correction in patients with PD, with similar patient satisfaction for the 2 groups. Habous M, Farag M, Tealab A, et al. Malleable Penile Implant Is an Effective Therapeutic Option in Men With Peyronie's Disease and Erectile Dysfunction. Sex Med 2017;X:XXX-XXX.

Sexual medicine. 2018 Jan 11 [Epub ahead of print]

Mohamad Habous, Alaa Tealab, Mohammed Farag, Tarek Soliman, Ben Williamson, Saad Mahmoud, Amin Elserafy, Zenhom Mekawi, Abdallah Remeah, Mohammed Nassar, Osama Laban, Osama Abdelwahab, Saleh Binsaleh, Simone Giona, David Ralph, John Mulhall

Elaj Medical Centers, Jeddah, Saudi Arabia. Electronic address: ., Urology Department, Zagazig University, Zagazig, Egypt., Urology Department, Al-Azhar Faculty of Medicine, Assiut, Egypt., Urology Department, Benha University, Benha, Egypt., University Hospitals Birmingham, Birmingham, UK., Elaj Medical Centers, Jeddah, Saudi Arabia., Urology Department, King Khaled Hospital, Tabouk, Saudi Arabia., Division of Urology, Department of Surgery, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia., King's College Hospital, London, UK., St Peter's Andrology Centre & The Institute of Urology, UCLH, London, UK., Sexual and Reproductive Medicine Program, Memorial Sloan Kettering Cancer Center, NY, USA.